I use through dowels frequently, but only on applications where they don’t show.
For example, I use them on face frame cabinets to strengthen the vertical panel to horizontal panel joints.
I use confirmats to “clamp” the joint, then i through drill and glue in dowels. The dowels provide racking strength and the confirmats hold thins together while the glue dries. But, those cabinets get end panels applied or they are hidden. No exposed joinery.